about IIS and the App Updater Blocks for .Net 1.1 and the Click Once stuff:
I would apply the MIME types only on the folder that will serv the updates.
other wise you might have files visible you don't want listed and other problems.
By clicking on the server node you add the type to *EVERY* domain / web / folder on that server.
Denny: Good point, I updated the post.
Roy,
This actually helped me solve a problem I was having today with ClickOnce - even though I was not getting the described error message. I couldn't figure out how ClickOnce decided to name the Start Menu folder for the installed app. It takes the Registered Organization - and you reg key in the post showed me how to change it.
Another problem (should be fixed at some stage) is that URLScan will deny any URLs with dots in them, so if you publish to a vdir such asa /foo/foo v1.0.0/ then URLScan will block the request.